[The effect of translam on the immune response of irradiated mice]

Radiats Biol Radioecol. 1995 Mar-Apr;35(2):260-3.
[Article in Russian]

Abstract

Experimental facts about influence of new beta-1-3;1-6-glucan, extracted from seaweed Laminaria, on immune response of mice are summarized. The ability of translam to increase the number and functional activity of immunocompetent cells taking part in humoral immune response formation. The possibility of translam using for treatment and prophylaxis of radiation affections is discussed.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Antigen-Antibody Reactions / drug effects*
  • Antigen-Antibody Reactions / immunology
  • B-Lymphocytes / drug effects
  • B-Lymphocytes / immunology
  • B-Lymphocytes / radiation effects
  • Cobalt Radioisotopes
  • Glucans / pharmacology*
  • Immunization
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred CBA
  • Polysaccharides / pharmacology*
  • Spleen / drug effects
  • Spleen / immunology
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / immunology
  • T-Lymphocytes / radiation effects
  • Time Factors

Substances

  • Cobalt Radioisotopes
  • Glucans
  • Polysaccharides
  • epiglucan
  • laminaran