Differential expression of Xenopus BMPs in early embryos and tissues

Zoolog Sci. 1993 Feb;10(1):175-8.


Expression levels of mRNA for Xenopus bone morphogenetic proteins (BMPs) in early embryos and adult organs were examined. Reverse transcription-polymerase chain reaction (RT-PCR) that used specific primers for each BMP subtype revealed that mRNAs for BMP-2 and BMP-4 are distributed in a wide variety of adult tissues including lung, heart, and kidney. Unexpectedly, distribution of mRNA for BMP-7 was found to be limited to ovary and early embryos. The result suggests that Xenopus BMP-7 may have a specific role in ovary and early embryos.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Bone Morphogenetic Proteins
  • Embryo, Nonmammalian / metabolism
  • Gene Expression Regulation*
  • Growth Substances / biosynthesis*
  • Growth Substances / genetics
  • Molecular Sequence Data
  • Protein Biosynthesis*
  • Proteins / genetics
  • Xenopus laevis / embryology*
  • Xenopus laevis / genetics


  • Bone Morphogenetic Proteins
  • Growth Substances
  • Proteins