Mass spectrometry of proteins and peptides in biotechnology

Curr Opin Biotechnol. 1993 Aug;4(4):412-9. doi: 10.1016/0958-1669(93)90006-i.


Recent technological developments in the field of mass spectrometry have resulted in enhanced performance in traditional biotechnological applications and are opening up new approaches to a wide range of problems in protein analysis. Developments in the area of interfacing mass spectrometry with high-resolution separation techniques and the observation of non-covalent interactions and protein conformational changes by mass spectrometry represent notable advances in the past year.

Publication types

  • Review

MeSH terms

  • Biotechnology
  • Mass Spectrometry
  • Peptides / chemistry*
  • Protein Binding
  • Protein Conformation
  • Proteins / chemistry*
  • Sequence Analysis


  • Peptides
  • Proteins