Antimicrobial sesquiterpenes from Prostanthera aff. melissifolia and P. rotundifolia

J E Dellar; M D Cole; A I Gray; S Gibbons; P G Waterman

doi:10.1016/s0031-9422(00)90471-0

Antimicrobial sesquiterpenes from Prostanthera aff. melissifolia and P. rotundifolia

Phytochemistry. 1994 Jul;36(4):957-60. doi: 10.1016/s0031-9422(00)90471-0.

Authors

J E Dellar¹, M D Cole, A I Gray, S Gibbons, P G Waterman

Affiliation

¹ Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, U.K.

PMID: 7765212
DOI: 10.1016/s0031-9422(00)90471-0

Abstract

Aerial material of Prostanthera aff. melissifolia and P. rotundifolia yielded three sesquiterpenes, two known compounds and a novel sesquiterpene, prostantherol. Prostantherol was identified as (rel)-1a alpha,3a beta,7a alpha,7b alpha-decahydro-4 beta-hydroxy- 1,1,4 alpha,7 alpha-tetramethylcyclopropa[a]-naphthalene on the basis of a comprehensive spectroscopic analysis. All three compounds were investigated for antimicrobial activity against phytopathogens.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Infective Agents / chemistry
Anti-Infective Agents / isolation & purification*
Anti-Infective Agents / pharmacology
Antifungal Agents / chemistry
Antifungal Agents / isolation & purification
Antifungal Agents / pharmacology
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Plants / chemistry*
Sesquiterpenes / chemistry
Sesquiterpenes / isolation & purification*
Sesquiterpenes / pharmacology

Substances

Anti-Infective Agents
Antifungal Agents
Sesquiterpenes