Levoglucosan dehydrogenase involved in the assimilation of levoglucosan in Arthrobacter sp. I-552

Biosci Biotechnol Biochem. 1994 Dec;58(12):2193-6. doi: 10.1271/bbb.58.2193.


A levoglucosan (1,6-anhydro-beta-D-glucopyranose)-using bacterium, isolated from soil, was identified. It was shown to belong to the genus Arthrobacter and tentatively named Arthrobacter sp. I-552. A novel enzyme catalyzed the dehydrogenation of levoglucosan to form 1,6-anhydro-beta-D-ribo-hexopyranos-3-ulose (3-keto levoglucosan), using NAD+ as an electron acceptor, i.e. NAD+: 1,6-anhydro-beta-D-glucopyranose oxidoreductase (trivial name: levoglucosan dehydrogenase). This enzyme was purified and characterized. A possible reaction scheme for the glucose formation was proposed. This pathway for levoglucosan use is distinct from those in yeast and fungi.

MeSH terms

  • Amino Acid Sequence
  • Arthrobacter / metabolism*
  • Glucose / analogs & derivatives*
  • Glucose / metabolism
  • Molecular Sequence Data
  • Sugar Alcohol Dehydrogenases / metabolism*


  • 1,6-anhydro-beta-glucopyranose
  • Sugar Alcohol Dehydrogenases
  • levoglucosan dehydrogenase
  • Glucose