Metoclopramide-induced sulfhemoglobinemia

Am J Gastroenterol. 1995 Jun;90(6):1010-1.


Metoclopramide, a drug with oxidant activity, has infrequently been reported to cause methemoglobinemia in infants. We present a unique case in which a patient on chronic metoclopramide therapy developed sulfhemoglobinemia that resolved with subsequent discontinuation of the drug. Mechanisms that may be important in the formation of sulfhemoglobin also are discussed.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Male
  • Metoclopramide / adverse effects*
  • Middle Aged
  • Sulfhemoglobinemia / chemically induced*


  • Metoclopramide