Isolation and characterization of the gene encoding the Drosophila melanogaster transcriptional elongation factor, TFIIS

Biochim Biophys Acta. 1995 May 17;1262(1):99-103. doi: 10.1016/0167-4781(95)00055-l.


We have characterized a genomic clone encoding the Drosophila melanogaster transcriptional elongation factor, TFIIS. The coding region of the TFIIS gene is interrupted by a short intron. The potential promoter region, deduced from the determination of the transcription start point (tsp), lacks distinct TATAAA or CCAAT box consensus sequences. Southern analysis and the in situ hybridization to chromosomes suggests that it is single-copy gene which is localized to the 35B region on the left arm of the second chromosome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Blotting, Southern
  • Chromosome Mapping
  • DNA, Complementary
  • Drosophila melanogaster / genetics*
  • Genes, Insect*
  • Molecular Sequence Data
  • Transcription Factors / genetics*
  • Transcription Factors, General*
  • Transcription, Genetic
  • Transcriptional Elongation Factors*


  • DNA, Complementary
  • Transcription Factors
  • Transcription Factors, General
  • Transcriptional Elongation Factors
  • transcription factor S-II

Associated data

  • GENBANK/L26091