Assembly of the postsynaptic apparatus

Curr Opin Neurobiol. 1995 Feb;5(1):62-7. doi: 10.1016/0959-4388(95)80088-3.

Abstract

Recent research has led to a clearer picture of the molecular organization of the postsynaptic apparatus at the developing neuromuscular junction. In addition, one link between the extracellular signaling molecule agrin and the intracellular events that mediate formation of acetylcholine receptor clusters has been established with the identification of an argin-binding protein.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Agrin / metabolism
  • Animals
  • Cytoskeletal Proteins / metabolism
  • Cytoskeletal Proteins / physiology
  • DNA, Complementary
  • Dystroglycans
  • Membrane Glycoproteins / physiology
  • Membrane Proteins*
  • Models, Molecular
  • Muscle Proteins / physiology
  • Neuromuscular Junction / physiology*
  • Receptors, Growth Factor / physiology
  • Receptors, Nicotinic / physiology
  • Synaptic Vesicles / physiology*
  • Utrophin

Substances

  • Agrin
  • Cytoskeletal Proteins
  • DNA, Complementary
  • Membrane Glycoproteins
  • Membrane Proteins
  • Muscle Proteins
  • Receptors, Growth Factor
  • Receptors, Nicotinic
  • Utrophin
  • agrin receptor
  • peripheral membrane protein 43K
  • Dystroglycans