The sensory-motor role of growth cone filopodia

Curr Opin Neurobiol. 1995 Feb;5(1):68-74. doi: 10.1016/0959-4388(95)80089-1.

Abstract

Neuronal growth cones, the motile tips of elongating axons and dendrites, respond very precisely to cues encountered during pathfinding. During the past year, our knowledge about their sensory function, their integrative properties, and their motor function has advanced significantly. In particular, growth cone filopodia are currently being recognized for their prominent roles as sensors, transducers, and autonomous motor structures important for growth cone steering.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Axons / physiology
  • Calcium / physiology
  • Chick Embryo
  • Dendrites / physiology
  • Ganglia, Sensory / growth & development
  • Ganglia, Sensory / physiology*
  • Motor Neurons / physiology*
  • Signal Transduction

Substances

  • Calcium