Fluoxetine hydrochloride (Prozac)-induced pulmonary disease

Chest. 1995 Jun;107(6):1763-5. doi: 10.1378/chest.107.6.1763.

Abstract

We describe a patient who developed progressive dyspnea, lung infiltrates, and restrictive lung disease in association with the antidepressant fluoxetine hydrochloride (Prozac). The pathologic findings were consistent with hypersensitivity pneumonitis. An associated pulmonary phospholipidosis was also noted.

Publication types

  • Case Reports

MeSH terms

  • Alveolitis, Extrinsic Allergic / chemically induced*
  • Alveolitis, Extrinsic Allergic / diagnostic imaging
  • Alveolitis, Extrinsic Allergic / metabolism
  • Alveolitis, Extrinsic Allergic / pathology
  • Drug Hypersensitivity*
  • Female
  • Fluoxetine / adverse effects*
  • Humans
  • Lung / diagnostic imaging
  • Lung / metabolism
  • Lung / pathology
  • Middle Aged
  • Phospholipids / metabolism
  • Radiography

Substances

  • Phospholipids
  • Fluoxetine