Epidemiology of human brucellosis in southern Saudi Arabia

J Trop Med Hyg. 1995 Jun;98(3):185-9.


There have been indications that human brucellosis is widely distributed in Saudi Arabia. In order to assess the situation in the south, and as a part of a nationwide prevalence survey, a sample of 4900 subjects was randomly selected for a house-to-house survey. Investigations included an interview, clinical examination and blood sampling for antibody titre determinations. Blood samples were first screened for Brucella antibodies by a microplate agglutination test to measure the exposed rate. Reactive sera were further analysed by the standard tube agglutination and 2-mercaptoethanol tests. A total of 4794 completed the study. Results of laboratory tests indicated that a significant proportion of the population in the southern region (19.2%) had serological evidence of exposure to Brucella antigen, and 2.3% had active disease. Direct contact with domestic animals and consumption of raw products of animal origin were identified as the main risk factors.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Animals
  • Animals, Domestic
  • Antigens, Bacterial / blood
  • Brucellosis / epidemiology*
  • Brucellosis / etiology
  • Brucellosis / immunology
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Prevalence
  • Random Allocation
  • Risk Factors
  • Sampling Studies
  • Saudi Arabia / epidemiology
  • Seroepidemiologic Studies
  • Sex Factors
  • Social Class


  • Antigens, Bacterial