The elusive fertility genes of Drosophila: the ultimate haven for selfish genetic elements

Trends Genet. 1995 May;11(5):195-200. doi: 10.1016/S0168-9525(00)89043-5.


The Y chromosomes of Drosophila are necessary for male fertility. They carry giant genes that have some unconventional properties besides controlling the motility of the spermatozoa. Classical genetic and molecular studies suggest that evolution has favoured the close association between these genes and repetitive DNA sequences with 'selfish' traits.

Publication types

  • Review

MeSH terms

  • Animals
  • Drosophila / genetics*
  • Drosophila / physiology
  • Fertility / genetics*
  • Genes, Insect*
  • Infertility, Male / genetics
  • Male
  • Y Chromosome / genetics