Refractory cardiogenic shock and complete heart block after verapamil SR and metoprolol treatment. A case report

Angiology. 1995 Jun;46(6):517-9. doi: 10.1177/000331979504600609.

Abstract

A seventy-eight-year-old woman presented with complete heart block and refractory hypotension two days after a therapeutic dose of sustained-release verapamil with concomitant use of metoprolol. The patient continued to remain hypotensive with complete heart block, even with multiple uses of intravenous atropine as well as high doses of pressor agents such as dopamine and dobutamine. However, shortly after the use of intravenous calcium chloride, the refractory hypotension and complete heart block resolved.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Delayed-Action Preparations
  • Drug Therapy, Combination
  • Emergencies
  • Female
  • Heart Block / chemically induced*
  • Heart Block / diagnosis
  • Heart Block / drug therapy
  • Humans
  • Hypertension / complications
  • Hypertension / drug therapy
  • Metoprolol / adverse effects*
  • Shock, Cardiogenic / chemically induced*
  • Shock, Cardiogenic / diagnosis
  • Shock, Cardiogenic / drug therapy
  • Verapamil / adverse effects*

Substances

  • Delayed-Action Preparations
  • Verapamil
  • Metoprolol