Vancomycin

Med Clin North Am. 1995 Jul;79(4):817-31. doi: 10.1016/s0025-7125(16)30041-4.

Abstract

Vancomycin is a nontoxic glycopeptide antibiotic most often used to treat serious gram-positive infections, C. difficile diarrhea/colitis, and endocarditis and hemodialysis shunt prophylaxis. Vancomycin should not be added to drug regimens for gram-positive coverage, and the empiric use of vancomycin should be discouraged to avoid the emergence of VRE. Vancomycin serum levels are no longer necessary or cost effective in most patients because vancomycin is not nephrotoxic.

Publication types

  • Review

MeSH terms

  • Bacterial Infections / drug therapy*
  • Drug Interactions
  • Gram-Negative Bacteria / drug effects
  • Gram-Positive Bacteria / drug effects
  • Humans
  • Microbial Sensitivity Tests
  • Vancomycin / adverse effects
  • Vancomycin / therapeutic use*

Substances

  • Vancomycin