Asymptomatic endemic rotavirus infections in the newborn

Lancet. 1978 Jun 3;1(8075):1176-8. doi: 10.1016/s0140-6736(78)90967-4.

Abstract

Between May 1, 1976, and May 14, 1977, 343 (32.5%) of 1056 5-day-old babies in newborn nurseries excreted rotaviruses. The infection-rate was highest during winter (49%). 76% of infected babies at this time were bottle-fed. 41% of neonates excreted low amounts of virus (less than or equal to 10(8) particles/g faeces); older children tended to excrete greater than 10(10) particles/g faeces. Infected breast-fed babies excreted less virus than those who were bottle-fed. Stools of breast-fed babies often contained clumps of complete "smooth" rotavirus particles. When the newborn nurseries were transferred to a newly built hospital wing, infection appeared in the new wards, including those admitting only new patients, within a short period. Infection was either mild (8%) or symptomless (92%), and even babies with symptoms required no treatment.

Publication types

  • Comparative Study

MeSH terms

  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • Diarrhea, Infantile / epidemiology
  • Diarrhea, Infantile / microbiology*
  • Feces / microbiology
  • Humans
  • Infant Nutritional Physiological Phenomena
  • Infant, Newborn
  • Infant, Newborn, Diseases / epidemiology
  • Infant, Newborn, Diseases / microbiology*
  • London
  • Nurseries, Hospital
  • Rotavirus / isolation & purification
  • Seasons
  • Virus Diseases / epidemiology
  • Virus Diseases / microbiology*