Clinical manifestations of genital infection due to Chlamydia trachomatis in women: differences related to serovar

Clin Infect Dis. 1994 Oct;19(4):756-60. doi: 10.1093/clinids/19.4.756.


The relationship between the infecting Chlamydia trachomatis serovar and the clinical manifestations of genital tract infection was evaluated in a study of 155 women attending a sexually transmitted diseases clinic; 99 women had lower genital tract infection and 56 had Chlamydia-associated pelvic inflammatory disease (PID). In the group with lower genital tract infection, women with serovar F differed from those with serovars of class B or C in that they exhibited fewer signs of cervical infection, including easily induced bleeding (P = .04), edema of the zone of cervical ectopy (P = .06), and colposcopic evidence of mucopurulent endocervical discharge (P = .007). Serovar F also produced fewer infections with inclusion counts of > or = 1,000 and fewer rectal infections (P = .04). There was no apparent association of any specific serovar with PID. Thus, in this population, serovar F was associated with fewer objective clinical manifestations of mucopurulent endocervical discharge, and the distribution of chlamydial serovars found in PID reflected that found in lower genital tract infection.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Chlamydia Infections* / diagnosis
  • Chlamydia Infections* / physiopathology
  • Chlamydia trachomatis / classification*
  • Chlamydia trachomatis / isolation & purification
  • Female
  • Genital Diseases, Female / diagnosis
  • Genital Diseases, Female / microbiology*
  • Genital Diseases, Female / physiopathology
  • Humans
  • Multivariate Analysis
  • Pelvic Inflammatory Disease / diagnosis
  • Pelvic Inflammatory Disease / microbiology*
  • Pelvic Inflammatory Disease / physiopathology
  • Serologic Tests
  • Serotyping