Effects of streptozotocin-induced diabetes on receptive and proceptive behaviors in female rats

Jikken Dobutsu. 1994 Oct;43(4):581-4. doi: 10.1538/expanim1978.43.4_581.


Sexual dysfunction in diabetic men is thoroughly recognized, while not yet done in diabetic women. Recently, Streptozotocin (STZ)-induced male rats showed a significantly depressed copulatory behavior, compared with normal animals. We investigated whether STZ-induced diabetic female rats would produce observable deficits in sexual behavior. Results in the present study are the first to show that STZ-induced diabetic female rats have a depressed sexual behavior.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Body Weight
  • Diabetes Mellitus, Experimental / physiopathology
  • Diabetes Mellitus, Experimental / psychology*
  • Female
  • Male
  • Rats
  • Rats, Wistar
  • Sexual Behavior, Animal*
  • Streptozocin


  • Streptozocin