Interactions of phenoxyl radical of antitumor drug, etoposide, with reductants in solution and in cell and nuclear homogenates: electron spin resonance and high-performance liquid chromatography

Methods Enzymol. 1994;234:631-42. doi: 10.1016/0076-6879(94)34134-6.
No abstract available

MeSH terms

  • Antioxidants / chemistry*
  • Antioxidants / pharmacology*
  • Ascorbic Acid / pharmacology
  • Azo Compounds
  • Cell Line
  • Cell Nucleus / metabolism*
  • Chromatography, High Pressure Liquid / methods
  • Electron Spin Resonance Spectroscopy / methods
  • Etoposide / chemistry*
  • Etoposide / pharmacology*
  • Free Radicals
  • Glutathione / pharmacology
  • Humans
  • Kinetics
  • Leukemia, Erythroblastic, Acute
  • Molecular Structure
  • Monophenol Monooxygenase / metabolism
  • Phenols*
  • Tumor Cells, Cultured

Substances

  • Antioxidants
  • Azo Compounds
  • Free Radicals
  • Phenols
  • phenoxy radical
  • Etoposide
  • Monophenol Monooxygenase
  • Glutathione
  • Ascorbic Acid