The torso pathway in Drosophila: lessons on receptor tyrosine kinase signaling and pattern formation

Dev Biol. 1994 Dec;166(2):380-95. doi: 10.1006/dbio.1994.1324.

Abstract

Pattern formation at the anterior and posterior termini of the Drosophila embryo involves intercellular communication via the Torso receptor tyrosine kinase (RTK). Recent advances in the understanding of Torso signaling has provided further support for the conservation of a signal transduction cassette downstream of RTKs. In addition, the analysis of the Torso pathway has begun to reveal general molecular mechanisms by which cells may impart patterning information to their neighbors through the use of RTKs.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Drosophila Proteins*
  • Drosophila melanogaster / embryology*
  • Drosophila melanogaster / genetics
  • Gene Expression Regulation, Developmental*
  • Genes, Insect
  • Morphogenesis
  • Oogenesis
  • Protein-Tyrosine Kinases / physiology*
  • Receptor Protein-Tyrosine Kinases / physiology*
  • Signal Transduction

Substances

  • Drosophila Proteins
  • Protein-Tyrosine Kinases
  • Receptor Protein-Tyrosine Kinases
  • tor protein, Drosophila