Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization

S Takai; Y Yoshida; M Noda; K Yamada; S Kumar

doi:10.1007/BF00225082

Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization

Hum Genet. 1995 Jan;95(1):96-8. doi: 10.1007/BF00225082.

Authors

S Takai¹, Y Yoshida, M Noda, K Yamada, S Kumar

Affiliation

¹ Department of Genetics, International Medical Center of Japan, Tokyo.

PMID: 7814034
DOI: 10.1007/BF00225082

Abstract

The developmentally regulated mouse gene Nedd 1 encodes a protein showing similarities with the beta-subunit of heterotrimeric GTP-binding proteins and has growth suppressing activity when overexpressed in various cultured cell types. We have mapped the human homolog (NEDD1) of the mouse gene to chromosome 12q22 by fluorescence in situ hybridization using R-banded human (pro)metaphase chromosomes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chromosome Banding
Chromosome Mapping
Chromosomes, Human, Pair 12*
DNA Damage
GTP-Binding Protein beta Subunits*
GTP-Binding Proteins / genetics*
Gene Expression Regulation, Developmental*
Heterotrimeric GTP-Binding Proteins*
Humans
In Situ Hybridization, Fluorescence
Mice
Microtubule-Associated Proteins
Nerve Tissue Proteins / genetics*

Substances

GTP-Binding Protein beta Subunits
Microtubule-Associated Proteins
Nerve Tissue Proteins
Nedd1 protein, mouse
GTP-Binding Proteins
Heterotrimeric GTP-Binding Proteins