Balanitis circumscripta plasmacellularis typically affects the glans penis and/or prepuce, and presents as chronic shiny smooth red-orange plaques. We report on an uncircumcised man with 2 moist red-orange lesions of balanitis circumscripta plasmacellularis on the glans and penile shaft, which were refractory to topical therapy and systemic antibiotics, and review the literature. Clinical morphology, microscopic features, differential diagnosis, postulated etiologies and treatments are discussed. When balanitis circumscripta plasmacellularis is suspected clinically, diagnosis can be readily confirmed by microscopic examination of the lesion. Differentiating this lesion from similar lesions is essential since it is benign and can be treated relatively easily by circumcision.