The brain beyond the synapse: a review

Neuroreport. 1994 Aug 15;5(13):1553-7. doi: 10.1097/00001756-199408150-00003.

Abstract

Several topics in contemporary neuroscience are treated in historical perspective. These include the localizationist-connectionist model of brain function and its influence on experimental neuroscience and clinical management of brain damaged persons; brain plasticity; the accumulating evidence for non-synaptic diffusion neurotransmission (NDN) as a major mechanism of information transmission in the brain; and the co-existence of plasticity and localization as well as of synaptic and non-synaptic mechanisms. The status of theory in the neurosciences is examined.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Brain / physiology*
  • Brain / ultrastructure
  • Humans
  • Synapses / physiology*
  • Synapses / ultrastructure