[Erythrokeratolysis hiemalis. Erythematosquamous genetic dermatosis with seasonal manifestation]

Hautarzt. 1994 Nov;45(11):776-9.
[Article in German]

Abstract

Erythrokeratolysis hiemalis, keratolytic winter erythema or Oudtshoorn skin has been reported from the South African district of Oudtshoorn as a dominantly inherited dermatosis beginning in early childhood, in some cases with circinar scaling erythemas. Seasonal manifestation in winter-time and a characteristic multi-form histology distinguish this dermatosis from other childhood scaling erythemas. We present clinical, histological and preliminary immunohistological data of a 4-year-old girl with the attributes of erythrokeratolysis hiemalis. No ancestors from the endemic region were traced. The lack of further cases in the family is interpreted as indicative of a spontaneous dominant new mutation.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Dermatitis, Exfoliative / diagnosis
  • Dermatitis, Exfoliative / genetics*
  • Dermatitis, Exfoliative / pathology
  • Female
  • Genes, Dominant
  • Humans
  • Immunohistochemistry
  • Leukocyte Common Antigens / genetics
  • Microscopy, Electron
  • Periodicity*
  • Seasons*
  • Skin / pathology

Substances

  • Leukocyte Common Antigens