Upper airway carriage by Haemophilus influenzae and Streptococcus pneumoniae in Australian aboriginal children hospitalised with acute lower respiratory infection

Southeast Asian J Trop Med Public Health. 1994 Mar;25(1):123-31.

Abstract

When nasopharyngeal secretions from 171 Australian Aboriginal children hospitalized with acute lower respiratory tract infections (ALRI) were cultured selectively for Streptococcus pneumoniae and Haemophilus influenzae, 136 (79.5%) and 151 (88.3%) children yielded 166 and 254 isolates of S. pneumoniae and H. influenzae, respectively. In colonized subjects multiple populations of S. pneumoniae (20% of carriage-positive patients) and H. influenzae (55%) were common. Pneumococci belonging to 27 types or groups were identified. H. influenzae serotype b colonized 16.4% of all children studied. More than one half of 152 children tested were excreting antibiotics at the time of admission to hospital. Significantly fewer children with serum antibiotic residues were colonized with S. pneumoniae than were antibiotic free children. Antibiotic usage had no measurable impact on the isolation rate of H. influenzae.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Anti-Bacterial Agents / blood
  • Anti-Bacterial Agents / therapeutic use
  • Carrier State / blood
  • Carrier State / drug therapy
  • Carrier State / ethnology*
  • Carrier State / microbiology*
  • Child
  • Child, Preschool
  • Continental Population Groups
  • Drug Monitoring
  • Drug Residues
  • Drug Utilization
  • Female
  • Haemophilus Infections / blood
  • Haemophilus Infections / drug therapy
  • Haemophilus Infections / ethnology*
  • Haemophilus Infections / microbiology*
  • Haemophilus influenzae* / classification
  • Hospitalization*
  • Humans
  • Infant
  • Infant, Newborn
  • Infection Control*
  • Male
  • Nasopharynx / microbiology*
  • Oceanic Ancestry Group*
  • Pneumococcal Infections / blood
  • Pneumococcal Infections / drug therapy
  • Pneumococcal Infections / ethnology*
  • Pneumococcal Infections / microbiology*
  • Respiratory Tract Infections / blood
  • Respiratory Tract Infections / drug therapy
  • Respiratory Tract Infections / ethnology*
  • Respiratory Tract Infections / microbiology*
  • Serotyping
  • Streptococcus pneumoniae / classification

Substances

  • Anti-Bacterial Agents