Treatment of early breast cancer

Lancet. 1978 Jul 1;2(8079):7-9. doi: 10.1016/s0140-6736(78)91320-x.


The early follow-up of patients treated by simple mastectomy alone or simple mastectomy combined with radical radiotherapy is presented. Both groups were well matched for age, menopausal status, duration of symptoms, size of tumour, and lymph-node involvement. There was no significant difference in survival of patients in the two groups at three years, but local recurrence was significantly more frequent (28%) in the mastectomy-alone patients. Early survival was not adversely affected by radiotherapy.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Age Factors
  • Aged
  • Breast Neoplasms / mortality
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / therapy*
  • Climacteric
  • Clinical Trials as Topic
  • Female
  • Follow-Up Studies
  • Humans
  • Lymphatic Metastasis
  • Male
  • Mastectomy*
  • Menopause
  • Middle Aged
  • Neoplasm Recurrence, Local / epidemiology
  • Postoperative Care
  • Radiotherapy, High-Energy
  • Time Factors