The sequence of a cDNA encoding the major vault protein from Rattus norvegicus

Gene. 1994 Dec 30;151(1-2):257-60. doi: 10.1016/0378-1119(94)90667-x.

Abstract

We have isolated a cDNA clone encoding the 104-kDa major vault protein (MVP) from Rattus norvegicus. The complete nucleotide sequence was determined. Comparison of the deduced amino acid (aa) sequence to that of MvpA from Dictyostelium discoideum revealed that the proteins share about 57% aa identity. Southern blot analysis indicates that the rat MVP is a single-copy gene.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Blotting, Southern
  • Cloning, Molecular
  • DNA, Complementary / biosynthesis
  • DNA, Complementary / chemistry
  • Dictyostelium / genetics
  • Fungal Proteins / genetics
  • Molecular Sequence Data
  • Molecular Weight
  • Protozoan Proteins*
  • Rats / genetics*
  • Ribonucleoproteins / biosynthesis
  • Ribonucleoproteins / genetics*
  • Sequence Homology, Amino Acid
  • Vault Ribonucleoprotein Particles*

Substances

  • DNA, Complementary
  • Fungal Proteins
  • MvpA protein, Dictyostelium discoideum
  • Protozoan Proteins
  • Ribonucleoproteins
  • Vault Ribonucleoprotein Particles
  • major vault protein

Associated data

  • GENBANK/U09870