The Respiratory System of Kluyveromyces Lactis Escapes From HAP2 Control

Gene. 1995 Jan 11;152(1):113-5. doi: 10.1016/0378-1119(94)00684-k.

Abstract

A functional homolog of the Saccharomyces cerevisiae HAP2 gene, coding for one element of a transcriptional activator complex, was cloned from the yeast Kluyveromyces lactis and its nucleotide sequence was determined. Inactivation of the gene had no significant effect on respiration-dependent growth, suggesting that the HAP2/3/4 complex has no major control over the formation of the mitochondrial respiratory system in K. lactis.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • CCAAT-Binding Factor*
  • Chromosomes, Fungal
  • Cloning, Molecular
  • Fungal Proteins / biosynthesis
  • Fungal Proteins / genetics*
  • Gene Dosage
  • Gene Expression Regulation, Fungal*
  • Genes, Fungal / genetics
  • Kluyveromyces / genetics*
  • Kluyveromyces / physiology
  • Mitochondria / genetics*
  • Mitochondria / physiology
  • Molecular Sequence Data
  • Mutagenesis
  • Oxygen Consumption / genetics*
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid
  • Transcription Factors / biosynthesis
  • Transcription Factors / genetics*

Substances

  • CCAAT-Binding Factor
  • Fungal Proteins
  • Transcription Factors

Associated data

  • GENBANK/U09272