The nucleotide sequence of the 5'non-coding and capsid coding genome regions of two bovine enterovirus strains

Arch Virol. 1994;139(3-4):287-99. doi: 10.1007/BF01310792.

Abstract

The sequence of cDNA clones representing the 5' non-coding regions (NCR) and capsid regions of two bovine enteroviruses (strains PS-87 and RM-2; serotype two viruses) have been determined and compared with that obtained from a serotype one strain (VG-5-27). All three strains showed a longer 5' NCR compared to human enteroviruses and rhinoviruses due in part to a hundred residue insertion approximately at a hundred residues in from the 5' end. However, another domain occurring at nucleotide 187-222 in poliovirus is absent in each bovine enterovirus. Comparisons of the predicted structural protein amino acid sequences indicate that PS-87 shares most sequence identity with RM-2 and then with VG-5-27 in that order. The VP1 protein of PS-87 and RM-2 are shorter than the equivalent VP1 of VG-5-27 due in part to a truncation at their C-terminii. VP3 is only slightly smaller than VP2 in each virus.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Capsid / chemistry
  • Capsid / genetics*
  • Cattle
  • Cloning, Molecular
  • Codon
  • DNA, Complementary / genetics
  • DNA, Viral / genetics
  • Enterovirus / genetics*
  • Genome, Viral*
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • Open Reading Frames
  • Sequence Alignment

Substances

  • Codon
  • DNA, Complementary
  • DNA, Viral

Associated data

  • GENBANK/X79368
  • GENBANK/X79369