Rheumatoid nodules and cyclosporin A treatment

Int J Clin Pharmacol Res. 1994;14(2):75-8.


The authors describe the appearance of rheumatoid nodules during cyclosporin A (CsA) therapy for RA. Their course was evaluated by sonography that revealed an increase in number and size of rheumatoid nodules. The relationship between CsA treatment and the onset of nodulosis is not clear and further studies are needed to assess the role of CsA treatment in the extra-articular manifestations of rheumatoid arthritis such as rheumatoid nodules.

Publication types

  • Case Reports

MeSH terms

  • Arthritis, Rheumatoid / complications
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / pathology
  • Cyclosporine / adverse effects*
  • Cyclosporine / therapeutic use
  • Female
  • Humans
  • Methylprednisolone / therapeutic use
  • Middle Aged
  • Rheumatoid Nodule / chemically induced*
  • Rheumatoid Nodule / diagnostic imaging
  • Ultrasonography


  • Cyclosporine
  • Methylprednisolone