Interhemispheric control of manual motor activity

Behav Brain Res. 1994 Oct 20;64(1-2):131-40. doi: 10.1016/0166-4328(94)90125-2.


The interhemispheric control of manual motor processes is reviewed, focusing on the clinical evidence from patients with commissurotomies and with agenesis of the corpus callosum. There is little evidence for a role of the corpus callosum in transferring explicit motor commands. Rather, the corpus callosum seems important for transferring lateralised information (such as verbal or visuospatial activity) of the pre-motor variety. Also, the corpus callosum may become very significant when movement begins: there appears to be a transcallosal passage of corollary motor signals and feedback sensory signals that are used to control asychronous bimanual movements and to inhibit the opposite hemisphere from interfering when a simple unimanual movement is required.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Attention / physiology*
  • Brain Mapping
  • Corpus Callosum / physiology*
  • Dominance, Cerebral / physiology*
  • Feedback / physiology
  • Functional Laterality / physiology*
  • Humans
  • Neural Pathways / physiology
  • Psychomotor Performance / physiology*