Differential reactivities of antibodies to HIV and HTLV-I in sera of suspected AIDS and ARC patients

West Afr J Med. 1994 Jul-Sep;13(3):150-1.

Abstract

Sera collection from 255 clinically diagnosed AIDS and ARC patients were analyzed for antibodies to HIV and HTLV-I by Western blot and particle agglutination methods respectively. Antibodies to HIV were detected in 37.3% of the sera collected as compared to 5.5% for HTLV-I. Most (95%) of the HIV positive sera had dual reactivity to both HIV-I and HIV-2. Antibodies to HTLV-1 were more frequently detected in HIV positive sera (11.58%) than in HIV negative sera (1.88%). Conversely, antibodies to HIV were detected twice as frequently in HTLV-1 positive sera (78.6%) than in HTLV-1 negative sera (34.85%).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS-Related Complex / diagnosis
  • AIDS-Related Complex / epidemiology
  • AIDS-Related Complex / immunology*
  • Acquired Immunodeficiency Syndrome / diagnosis
  • Acquired Immunodeficiency Syndrome / epidemiology
  • Acquired Immunodeficiency Syndrome / immunology*
  • Blotting, Western
  • Ghana / epidemiology
  • HIV Antibodies / blood*
  • HIV Seroprevalence
  • HTLV-I Antibodies / blood*
  • Humans
  • Population Surveillance
  • Seroepidemiologic Studies

Substances

  • HIV Antibodies
  • HTLV-I Antibodies