5' noncoding sequence of human IL-10 gene obtained by oligo-cassette PCR walking

DNA Seq. 1994;4(6):399-401. doi: 10.3109/10425179409010188.


A fragment of the human IL-10 gene starting from a Hind III site and including 744 previously unknown bases of the 5' regulatory region was isolated by oligo-cassette PCR walking and the nucleotide sequence was determined. It shows remarkable homology to the mouse IL-10 promoter in regions that have been associated with transcriptional regulation.

MeSH terms

  • Animals
  • Base Sequence
  • DNA
  • Humans
  • Interleukin-10 / genetics*
  • Mice
  • Molecular Sequence Data
  • Polymerase Chain Reaction / methods*
  • Sequence Analysis, DNA / methods*
  • Sequence Homology, Nucleic Acid


  • Interleukin-10
  • DNA

Associated data

  • GENBANK/X73536