Longitudinal study of visual functions in young insulin dependent diabetics

Ophthalmic Physiol Opt. 1994 Oct;14(4):339-46.


The aim of this study was to compare the visual functions of a group of young insulin dependent diabetes mellitus patients (IDDMs), (n = 42) with an age and sex matched control group (n = 24). Examinations were carried out every 3 months for 2 years. There were no significant differences in visual acuity between IDDMs and control subjects. The IDDMs made significantly more errors with the desaturated D15 compared with the control group (P < 0.05). The contrast sensitivity for the IDDMs was lower at each spatial frequency compared with the control group, being significantly different from 3 c/deg and above (P < 0.05). A negative correlation was found between HbA1 and contrast sensitivity at 6 and 12 c/deg; as the HbA1 increased the contrast sensitivity decreased (P < 0.05). As the blood glucose level decreased, the colour vision deteriorated (P < 0.05). There was no significant difference between the visual performance of those IDDMs with retinopathy (n = 5) compared to those without.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Blood Glucose / metabolism
  • Child
  • Color Perception / physiology
  • Contrast Sensitivity
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / physiopathology*
  • Diabetic Retinopathy / diagnosis
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Vision, Ocular / physiology*
  • Visual Acuity


  • Blood Glucose