Case of occupational asthma due to glue containing cyanoacrylate

Ann Acad Med Singap. 1994 Sep;23(5):731-3.


Cyanoacrylates are a rare cause of occupational asthma, there being only six cases reported previously. High humidity has been implicated to be protective in the pathogenesis of the asthma. This is a case report of occupational asthma due to cyanoacrylate glue after working three years in a factory manufacturing doors. Diagnosis was made by history, serial peak flow measurements on and off work and specific inhalation challenge which elicited a delayed bronchoconstrictive response. An unusual feature of this case was the positive reaction to cyanoacrylate despite the high ambient humidity in Singapore.

Publication types

  • Case Reports

MeSH terms

  • Adhesives / adverse effects*
  • Adult
  • Asthma / chemically induced*
  • Asthma / diagnosis
  • Bronchial Provocation Tests
  • Cyanoacrylates / adverse effects*
  • Female
  • Humans
  • Occupational Diseases / chemically induced*
  • Occupational Diseases / diagnosis
  • Peak Expiratory Flow Rate
  • Singapore
  • Spirometry


  • Adhesives
  • Cyanoacrylates