Abstract
An automatic data processing and display protocol for proton magnetic resonance spectroscopic imaging is described. The spectroscopic images are generated using the fitted peak areas of phased metabolite resonances using the Levenberg-Marquardt algorithm. This automated spectroscopic image processing is tested and evaluated using phantom and human brain data. This algorithm is robust, simple to use, and minimizes user bias in processing and quantifying serial changes of metabolite levels in brain tissue.
Publication types
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Algorithms*
-
Aspartic Acid / analogs & derivatives
-
Aspartic Acid / metabolism
-
Bias
-
Brain / metabolism
-
Cerebrospinal Fluid / metabolism
-
Choline / metabolism
-
Creatine / metabolism
-
Data Display
-
Electron Spin Resonance Spectroscopy
-
Electronic Data Processing
-
Humans
-
Image Processing, Computer-Assisted* / methods
-
Magnetic Resonance Spectroscopy* / methods
-
Male
-
Models, Structural
-
Protons
Substances
-
Protons
-
Aspartic Acid
-
N-acetylaspartate
-
Creatine
-
Choline