Lung cancer pathology in smokers, ex-smokers and never smokers

Cancer Lett. 1995 Jan 6;88(1):1-5. doi: 10.1016/0304-3835(94)03608-l.


The histologic distribution of lung cancer is markedly different in smokers and non-smokers. It is not known whether the histology among former smokers varies according to the number of years since quitting. Using data from a large case-control study of lung cancer, we found that for both men and women, the proportion of adenocarcinomas increased with the number of years since quitting smoking. Among long-term quitters (> 25 years), the proportion of adenocarcinomas was similar to that in never smokers. These findings have implications for studies of environmental tobacco smoke and lung cancer.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenocarcinoma / epidemiology*
  • Adult
  • Aged
  • Carcinoma, Squamous Cell / epidemiology*
  • Case-Control Studies
  • Female
  • Humans
  • Lung Neoplasms / epidemiology*
  • Male
  • Middle Aged
  • Smoking*
  • Social Class
  • Time Factors