The healing and incorporation of intercalary cortical bone allografts stabilized with locked intramedullary nails was compared with that of allografts fixed with compression plates in a sheep model. Both techniques achieved healing of the allograft to host tibia, and there was no measurable difference in the area of callus or the quality of union histologically. Incorporation of the allograft as measured by fluorescent labeling was not different in the two groups.