Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
, 45 (2), 384-5

Frequency of Anti-Nuclear Antibodies in Multiple Sclerosis

Affiliations
Comparative Study

Frequency of Anti-Nuclear Antibodies in Multiple Sclerosis

S Barned et al. Neurology.

Abstract

We found anti-nuclear antibodies (ANA) in 26.7% of 150 relapsing-remitting and in 30.4% of 23 chronic progressive definite multiple sclerosis (MS) patients by retrospective chart review. These patients did not have systemic lupus erythematosus. Since ANA are not pathogenically relevant in MS, they are false-positive, and likely reflect systemic immune dysregulation in MS.

Comment in

Similar articles

  • Frequency and Significance of Antinuclear Antibodies in Multiple Sclerosis
    RC Collard et al. Neurology 49 (3), 857-61. PMID 9305354.
    In a prospective sample of patients with multiple sclerosis (MS) we found a high frequency of antinuclear antibodies (ANA), 22.5%, confirming results from previous studie …
  • [Antinuclear Antibodies in Multiple Sclerosis]
    A Antigüedad et al. Neurologia 12 (6), 245-8. PMID 9303591.
    The prevalence of circulating antinuclear antibodies (ANA) was studied in a group of 147 patients with multiple sclerosis (MS). Also analyzed was the evolution of ANA ove …
  • [Antibodies to Native and Denatured DNA in Multiple Sclerosis]
    VM Alifirova et al. Zh Nevrol Psikhiatr Im S S Korsakova 111 (2 Pt 2), 16-20. PMID 21916154.
    An aim of the present paper was to study antibodies to native and denatured DNA in the serum of patients with multiple sclerosis (MS). Sixty-two patients and 27 healthy p …
  • Lupoid Sclerosis
    B Keiserman et al. Rheumatol Int 30 (4), 431-4. PMID 19826821. - Review
    Lupoid sclerosis (LS) is a controversial entity, comprising features of both systemic lupus erythematosus and multiple sclerosis. Diagnostic criteria are a matter of deba …
  • [Antinuclear Antibodies Without Connective Tissue Disease : Antibodies Against LEDGF/DSF70]
    R Mierau. Z Rheumatol 75 (4), 372-80. PMID 26820723. - Review
    Testing for antinuclear antibodies (ANA) by the indirect immunofluorescence test (IFT) is regarded as a fundamental serological screening method for diagnosing connective …
See all similar articles

Cited by 8 PubMed Central articles

See all "Cited by" articles

Publication types

Substances

LinkOut - more resources

Feedback