X-ray characterization of melanins--II

Pigment Cell Res. 1994 Aug;7(4):263-73. doi: 10.1111/j.1600-0749.1994.tb00061.x.


Structural modeling of amorphous eumelanin has been carried out by comparing calculated data, S(q) and RDF(r), in reciprocal and real space, respectively, for limited random network models with the experimental X-ray scattering data of tyrosine melanin (Cheng et al., 1994). A basic picture of the atomic arrangements in amorphous eumelanin, which accounts for the short and intermediate range order, has been formulated. This reveals domains of a fundamental "particle" dimension of R approximately 15 A, consisting of a paracrystalline array of disordered planar networks polymerized by 4-8 DHI monomers with a graphite-like stacking spacing of approximately 3.45 A, 4-5 layers thick.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Chemical Phenomena
  • Chemistry, Physical
  • Fourier Analysis
  • Mathematics
  • Melanins / chemistry*
  • Models, Molecular
  • Molecular Structure
  • Scattering, Radiation
  • Tyrosine
  • X-Rays


  • Melanins
  • eumelanin
  • Tyrosine