Bioenergetics in clinical medicine. VI. adjunctive treatment of periodontal disease with coenzyme Q10

Res Commun Chem Pathol Pharmacol. 1976 Aug;14(4):715-9.

Abstract

Eighteen patients with periodontal disease and measurable pockets were treated on a double-blind basis with coenzyme Q10 and a maching placebo. The treatment was significant (p less than 0.01). Before decoding, all 8 patients receiving coenzyme Q10 and 7/10 patients receiving placebo were correctly assigned. Of the remaining 3 placebo patients, the status of one was borderline and could have been assigned to either group, and two improved due to better hygiene. Crevicular fluid flow as a measure of inflammation was newly monitored. Pocket-depth, periodontal health, calculus and plaque scores provided the most valuable data for evaluation.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Clinical Trials as Topic
  • Gingiva / pathology
  • Humans
  • Periodontal Diseases / drug therapy*
  • Periodontal Diseases / pathology
  • Placebos
  • Time Factors
  • Ubiquinone / adverse effects
  • Ubiquinone / therapeutic use*

Substances

  • Placebos
  • Ubiquinone