Clinical investigation of the antidepressant effectiveness of hypericum

J Geriatr Psychiatry Neurol. 1994 Oct;7 Suppl 1:S6-8. doi: 10.1177/089198879400700103.

Abstract

To date, 25 controlled therapy studies have investigated the antidepressive effectiveness of hypericum extracts. A total of 1592 treatment cases have been included. The dosage was typically 300 to 900 mg total extract daily; the therapy duration was 2 to 6 weeks. Fifteen studies were performed comparing hypericum extracts with placebo, 10 studies as comparative studies. This paper presents an overview of their results.

Publication types

  • Meta-Analysis

MeSH terms

  • Antidepressive Agents / therapeutic use*
  • Humans
  • Hypericum
  • Perylene / analogs & derivatives*
  • Perylene / therapeutic use
  • Plant Extracts / therapeutic use*
  • Plants, Medicinal
  • Quercetin / analogs & derivatives*
  • Quercetin / therapeutic use
  • Xanthenes / therapeutic use*

Substances

  • Antidepressive Agents
  • Plant Extracts
  • Xanthenes
  • Perylene
  • Quercetin