Tranexamic acid (AMCA) and late hyphaema. A double blind study in cataract surgery

Acta Ophthalmol (Copenh). 1976 Aug;54(4):417-29. doi: 10.1111/j.1755-3768.1976.tb01273.x.

Abstract

A double blind study of the effect of tranexamic acid (AMCA) on late hyphaema after cataract surgery is reported. A total of 244 patients were included in the study after strict selection. It was shown that the incidence of late hyphaema in the treated group was significantly lower at the 5% level than that in the placebo group. The conclusion is made that the fibrinolytic inhibitor tranexamic acid can be used therapeutically or prophylactically to decrease the risk for re-bleeding after ocular surgery.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Oral
  • Cataract Extraction*
  • Clinical Trials as Topic
  • Cyclohexanecarboxylic Acids / therapeutic use*
  • Drug Evaluation
  • Humans
  • Hyphema / prevention & control*
  • Postoperative Complications / prevention & control*
  • Tranexamic Acid / administration & dosage
  • Tranexamic Acid / adverse effects
  • Tranexamic Acid / therapeutic use*

Substances

  • Cyclohexanecarboxylic Acids
  • Tranexamic Acid