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Clinical Trial
, 54 (2), 150-60

Piracetam-induced Improvement of Mental Performance. A Controlled Study on Normally Aging Individuals

Clinical Trial

Piracetam-induced Improvement of Mental Performance. A Controlled Study on Normally Aging Individuals

P Mindus et al. Acta Psychiatr Scand.

Abstract

A double-blind, intra-individual cross-over comparison of the mental performance of 18 aging, non-deteriorated individuals during two 4-week periods of piracetam (1-acetamide-2-pyrrolidone) and placebo administration was performed using conventional and computerized perceptual-motor tasks. In a majority of these tasks the subjects did significantly better when on piracetam than on placebo, a finding consistent with ratings completed by two independent observers. The findings indicate new avenues for the treatment of individuals with reduced mental performance possibly related to disturbed alertness--a neglected group of psychiatric conditions.

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