[Hyperthyroidism and hypersecretion of chorionic gonadotropin in gastric adenocarcinoma]

Rev Med Interne. 1994;15(12):830-3. doi: 10.1016/s0248-8663(05)82840-1.
[Article in French]

Abstract

We report a case of hyperthyroidism complicating and revealing a metastatized adenocarcinoma of the stomach with high circulating levels of human chorionic gonadotropin and its beta component. To our knowledge, this is the first reported case of a non-trophoblastic tumor with hyperthyroidism and secreting quantities of these hormones. High circulating levels of beta component in such patients have been considered to be a sign of malignancy. The mechanisms of thyroid stimulation could be related to the biological activity of certain forms of the human chorionic gonadotropin.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / complications
  • Adenocarcinoma / metabolism*
  • Chorionic Gonadotropin / metabolism*
  • Humans
  • Hyperthyroidism / etiology*
  • Male
  • Middle Aged
  • Stomach Neoplasms / complications
  • Stomach Neoplasms / metabolism*

Substances

  • Chorionic Gonadotropin