Partial characterization of the molecular species of phosphatidylserine from human plasma by high-performance liquid chromatography and fast atom bombardment mass spectrometry

S Chen

doi:10.1016/0378-4347(94)00337-8

Partial characterization of the molecular species of phosphatidylserine from human plasma by high-performance liquid chromatography and fast atom bombardment mass spectrometry

J Chromatogr B Biomed Appl. 1994 Nov 4;661(1):1-5. doi: 10.1016/0378-4347(94)00337-8.

Author

S Chen¹

Affiliation

¹ Department of Chemistry, University of Warwick, Coventry, UK.

PMID: 7866537
DOI: 10.1016/0378-4347(94)00337-8

Abstract

Phosphatidylserine from human plasma was purified and identified by amino normal-phase and octadecylsilyl reversed-phase high-performance liquid chromatography, respectively. The two major molecular species within the human plasma phosphatidylserine, qualitatively determined by negative-ion fast atom bombardment mass spectrometry, are 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoserine and 1-stearoyl-2-arachidonyl-sn-glycero-3-phosphoserine.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Chromatography, High Pressure Liquid / methods*
Chromatography, Ion Exchange
Humans
Male
Phosphatidylserines / blood*
Phosphatidylserines / chemistry
Phosphatidylserines / isolation & purification
Spectrometry, Mass, Fast Atom Bombardment / methods*

Substances

Phosphatidylserines