Ovadendron sulphureo-ochraceum endophthalmitis after cataract surgery

Am J Ophthalmol. 1995 Mar;119(3):307-12. doi: 10.1016/s0002-9394(14)71172-9.


Purpose: We examined an 82-year-old woman with delayed-onset endophthalmitis caused by an opportunistic pathogen, Ovadendron sulphureo-ochraceum.

Methods: Tissue obtained during vitrectomy was cultured and examined by light and electron microscopy. An enucleation specimen was examined by light microscopy.

Results: The patient had fungal endophthalmitis, with O. sulphureo-ochraceum present in the lens capsule. The eye developed a necrotizing scleritis secondary to O. sulphureo-ochraceum. The patient failed to respond to intravitreous, subconjunctival, and systemic amphotericin B, and the eye was enucleated.

Conclusion: In this case of O. sulphureo-ochraceum as a human pathogen, the organism caused endophthalmitis after cataract extraction.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Amphotericin B / administration & dosage
  • Cataract Extraction / adverse effects*
  • Endophthalmitis / drug therapy
  • Endophthalmitis / microbiology*
  • Endophthalmitis / pathology
  • Eye Enucleation
  • Eye Infections, Fungal* / drug therapy
  • Female
  • Humans
  • Lens Capsule, Crystalline / microbiology
  • Lenses, Intraocular
  • Mitosporic Fungi / isolation & purification*
  • Mitosporic Fungi / ultrastructure
  • Mycoses* / drug therapy
  • Vitrectomy
  • Vitreous Body / microbiology


  • Amphotericin B