Review
doi: 10.1038/374131a0.
Principles of CDK regulation
Affiliations
- PMID: 7877684
- DOI: 10.1038/374131a0
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Review
Principles of CDK regulation
Nature.
.
Abstract
As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.
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