T lymphocytes and immunosuppression in the burned patient: a review

Burns. 1994 Dec;20(6):487-90. doi: 10.1016/0305-4179(94)90002-7.


Extensive thermal trauma results in impaired immune function which has been attributed to a reduction in T lymphocyte numbers, increased suppressor cell activity, serum suppressive factors and altered cytokine synthesis and receptor expression on T cells. Numeric and phenotypic changes in T lymphocytes, T cell proliferation and functional responses of T lymphocytes in recent studies using murine models and patients are described.

Publication types

  • Review

MeSH terms

  • Animals
  • Burns / immunology*
  • Burns / physiopathology
  • Humans
  • Immune Tolerance*
  • Immunocompromised Host / immunology
  • Immunocompromised Host / physiology
  • Lymphopenia
  • T-Lymphocytes / immunology*
  • T-Lymphocytes / physiology