Focal adhesion kinase: structure and signalling

J T Parsons; M D Schaller; J Hildebrand; T H Leu; A Richardson; C Otey

doi:10.1242/jcs.1994.supplement_18.16

Focal adhesion kinase: structure and signalling

J Cell Sci Suppl. 1994:18:109-13. doi: 10.1242/jcs.1994.supplement_18.16.

Authors

J T Parsons¹, M D Schaller, J Hildebrand, T H Leu, A Richardson, C Otey

Affiliation

¹ Department of Microbiology, University of Virginia, Charlottesville 22908.

PMID: 7883785
DOI: 10.1242/jcs.1994.supplement_18.16

Abstract

Studies on the attachment and spreading of cells in culture have provided valuable insights into the mechanisms by which cells transmit information from the outside to the inside of the cell. This brief review considers recent information on the role of focal adhesion-associated protein tyrosine kinases in integrin-regulated cell signalling.

Publication types

Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Amino Acid Sequence
Animals
Cell Adhesion Molecules / chemistry
Cell Adhesion Molecules / physiology*
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
Humans
Integrins / physiology
Molecular Sequence Data
Protein-Tyrosine Kinases / chemistry
Protein-Tyrosine Kinases / physiology*
Signal Transduction / physiology*

Substances

Cell Adhesion Molecules
Integrins
Protein-Tyrosine Kinases
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
PTK2 protein, human

Abstract

Publication types

MeSH terms

Substances

Grants and funding