Technetium Tc 99m sestamibi scan for localizing abnormal parathyroid glands after previous neck operations: preliminary experience in reoperative cases

South Med J. 1995 Mar;88(3):327-30. doi: 10.1097/00007611-199503000-00016.


We used technetium Tc 99m sestamibi for successful preoperative localization of abnormal parathyroid glands in nine patients with hyperparathyroidism and a history of neck surgery. The intraoperative and pathological findings were correlated with the preoperative technetium-sestamibi scan results. These nine patients had had 13 previous neck operations, two for thyroid disease, and 11 for hyperparathyroidism. In the two operated on for thyroid disease, the 99mTc-sestamibi scan localized a parathyroid adenoma. In one patient, the three remaining hyperplastic parathyroid glands were localized using 99mTc-sestamibi scan. The other six patients had 10 operations for hyperparathyroidism; the 99mTc-sestamibi scan localized the remaining parathyroid glands causing hypercalcemia. In this preliminary experience, the 99mTc-sestamibi scan localized all the abnormal parathyroid glands causing hyperparathyroidism in patients who had previously had neck surgery.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Hyperparathyroidism / diagnostic imaging*
  • Hyperparathyroidism / surgery
  • Hyperplasia
  • Male
  • Middle Aged
  • Parathyroid Glands / diagnostic imaging
  • Parathyroid Glands / pathology*
  • Preoperative Care
  • Prospective Studies
  • Radionuclide Imaging
  • Reoperation
  • Technetium Tc 99m Sestamibi*


  • Technetium Tc 99m Sestamibi